GermOnline, a cross-species community knowledgebase on germ cell differentiation

Author(s)

Christa Wiederkehr, R Basavaraj, C Sarrauste de Menthiere, Leandro Hermida, R. Koch, Ulrich Schlecht, Angelika Amon, Sophie Brachat, Michael Breitenbach, Peter Briza, S Caburet, Maria Cherry, Robert Davis, Adam M. Deutschbauer, Hugh G. Dickinson, Teodora Pene Dumitrescu, Marc Fellous, A Goldman, J. Anton Grootegoed, R. Scott Hawley, R Ishii, Bernard Jegou, Randal J. Kaufman, Franz Klein, N Lamb, Bernard Maro, Kim Nasmyth, Alain Nicolas, Terry L. Orr-Weaver, Peter Philippsen, Charles P. Pineau, Kirsten P Rabitsch, Valerie Reinke, Henk P. Roest, William S. Saunders, Martin Schröder, Tim Schedl, Michel Siep, Anne M. Villeneuve, Debra J. Wolgemuth, M Yamamoto, Denise Zickler, Rochelle Easton Esposito, Michael Primig

Abstract

GermOnline provides information and microarray expression data for genes involved in mitosis and meiosis, gamete formation and germ line development across species. The database has been developed, and is being curated and updated, by life scientists in cooperation with bioinformaticists. Information is contributed through an online form using free text, images and the controlled vocabulary developed by the GeneOntology Consortium. Authors provide up to three references in support of their contribution. The database is governed by an international board of scientists to ensure a standardized data format and the highest quality of GermOnline's information content. Release 2.0 provides exclusive access to microarray expression data from Saccharomyces cerevisiae and Rattus norvegicus, as well as curated information on ~700 genes from various organisms. The locus report pages include links to external databases that contain relevant annotation, microarray expression and proteome data. Conversely, the Saccharomyces Genome Database (SGD), S.cerevisiae GeneDB and Swiss-Prot link to the budding yeast section of GermOnline from their respective locus pages. GermOnline, a fully operational prototype subject-oriented knowledgebase designed for community annotation and array data visualization, is accessible at www.germonline.org. The target audience includes researchers who work on mitotic cell division, meiosis, gametogenesis, germ line development, human reproductive health and comparative genomics.

Organisation(s)

Department of English and American Studies, Department of Social and Cultural Anthropology, Department of Botany and Biodiversity Research

External organisation(s)

Université de Lausanne, Universität Basel, Institut de Génétique Humaine, Massachusetts Institute of Technology, Paris-Lodron Universität Salzburg, Hopital Cochin, Stanford University, University of Oxford, University of Pittsburgh, Institut national de la santé et de la recherche médicale (INSERM), University of Sheffield, Erasmus University Rotterdam, University of Kansas, University of Tokyo, Université Rennes-I, Case Western Reserve University, Université Paris VI - Pierre-et-Marie-Curie, Vienna BioCenter , Yale University, Technische Universität Darmstadt, Washington University in St. Louis, Columbia University in the City of New York, Université Paris XI - Paris-Sud, University of Chicago

Journal

Nucleic Acids Research

Volume

32

Pages

560-567

No. of pages

8

ISSN

0305-1048

Publication date

2004

Peer reviewed

Yes

Austrian Fields of Science 2012

1060 Biology

Sustainable Development Goals

SDG 3 - Good Health and Well-being

Portal url

https://ucrisportal.univie.ac.at/en/publications/germonline-a-crossspecies-community-knowledgebase-on-germ-cell-differentiation(d9fe1057-f526-493b-811a-af08d40984e8).html